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Affected infants may also display low birth weight, growth deficiencies, diminished muscle tone (hypotonia), and microcephaly, a condition that indicates that head circumference is smaller than would be expected for an infant’s age and sex.

Distinctive facial features may include an abnormally round or plump (moon) face, a broad nasal bridge, widely spaced eyes (hypertelorism), crossed eyes (strabismus), downwardly slanting eyelid folds (palpebral fissures), vertical skin folds that may cover the eyes’ inner corners (epicanthal folds), low-set ears, and an abnormally small jaw (micrognathia).

Most affected infants also display some degree of psychomotor and intellectual disability.

Psychomotor disability is a delay in the acquisition of skills requiring mental and muscular activities such head control, sitting up, and walking.

That’s the promise from Bumble, an 8-month-old app that’s adding a new algorithm to grade users on metrics like engagement and, well, whether they’re demanding to see you naked.

To earn a “VIBee” badge on Bumble, male and female users alike must establish a track record of having real conversations with other users, says Whitney Wolfe, Bumble’s founder and CEO.

Improper alignment of the upper and lower teeth (malocclusion) may also occur.

Additional facial features include an abnormally small distance from the upper lip to the nose (short philtrum), incomplete closure of the roof of the mouth (cleft palate), an abnormal groove or gap in the upper lip (cleft lip), and abnormal fullness of the lower lip.

The cry, which resembles the mewing of a cat, becomes less pronounced as affected infants grow older.“I personally can tell you that all my girlfriends — and many women I’ve spoken to — have this fear of being perceived as desperate or forward when they want to approach a man,” Wolfe said.“It was always, ‘He must text you first’ — but why?Bumble isn’t releasing figures on its active user base, but after passing the 500,000 mark two or three months ago, it has been growing at a week-over-week clip of as much as 15 percent. Design has been started (for real this time) and is underway.

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